Tag Archives: Egg Freezing Technology

ESHRE Endorses Egg Freezing : ASRM Lifts Experimental Label From Egg Freezing

The American Society of Reproductive Medicine (ASRM) and the European Society of Human Reproduction and Embryology (ESHRE) have endorsed oocyte freezing as a standard and safe procedure in  2012. ASRM  issued a new report on 22 October, 2012 stating that in young patients egg freezing techniques have been shown to produce pregnancy rates, leading to the birth of healthy babies, comparable to IVF cycles using fresh eggs. After much work and deliberation by fertility experts, who reviewed the world literature on the effectiveness and safety of egg freezing and, most importantly, on the desired outcome: healthy babies, egg freezing is can now be used in routine practice. More studies are being published regarding this age range, and all is reassuring.



Egg freezing could provide a viable alternative source for couples needing donor eggs to build their families. In addition, among the medical indications for its use are fertility preservation for patients who may be left infertile following medical treatments for other diseases  (viz., cancer),  some genetic conditions, or IVF treatment interrupted by the unexpected inability to obtain sperm.Cryotec



The Committee points out that the age of the woman at the time of egg freezing is a very important factor. “Success rates with oocyte cryopreservation appear to decline with maternal age consistent with the clinical experience with fresh oocytes.”  ASRM did not encourage egg freezing for “social reasons,” such as a delay in childbearing as, although the technical procedure of egg freezing is safe, we do not have enough long-term data about babies born to women using eggs frozen when they are older than 35. Cryotec VitrificationCiting a lack of data on safety, efficacy, cost-effectiveness, and potential emotional risks, the report states, “Marketing this technology for the purpose of deferring childbearing may give women false hope and encourage women to delay childbearing. Patients who wish to pursue this technology should be carefully counseled.”



Rotunda is now offering oocyte cryopreservation as part of its ART services  using the latest cutting edge Cryotec vitrification technique. We also have initiated donor egg bank. We have achieved comparable success rates with frozen donor oocytes  to fresh donor oocytes.

Rotunda Egg Freezing ProgramThe excellent survival rates, embryo development and pregnancy rates have given a tremendous new hope to young cancer women. These young cancer patients can now dream of becoming a mother one day in future when they are cured of their disease.


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IVF successes break new reproductive ground

Despite IVF being used for thirty years, fertility treatments are still breaking new ground to assist couples struggling to conceive children – in multiples. Recently the first US babies conceived using frozen eggs were born in Minnesota and now quadruplets have been born in California to two mothers within a same-sex partnership.

After two unsuccessful IVF cycles and a miscarriage, Ceresa and Jonathan Caudill succeeded in having the first babies in Minnesota to be born from frozen eggs rather than embryos. In California, partners Karen Wesolowski, 42, and Martha Padgett, 38, underwent fertility treatments for between three and four years, spending roughly £35,000 on five cycles of IVF, before having the first reported quadruplets to ever be born two mothers when they each had twins using IVF embryos created from Padgett’s eggs and a sperm donor.

The egg-freezing technology which successfully led to the birth of the Caudill’s twin daughters is an imperfect science. The egg is the body’s largest cell and, unlike sperm and embryos, is predominantly composed of water which crystallises during the freezing process and can damage it. Experts hope that, once reliable, the technique could significantly help women to control their reproductive destinies. Researchers posture that the technology could impact reproductive choice in much the same way that the birth control pill did forty years ago. ‘For women who are sure they are going to go through menopause from cancer treatments, or for women in their mid-30s who don’t see a partner on the horizon, there really aren’t other options’, said Dr. Elizabeth Ginsberg, president-elect of the Society for Assisted Reproductive Technology (SART) and a fertility doctor in Boston.
According to Dr. Charles Coddington who heads the Mayo fertility clinic in Rochester, many couples like the Caudills do not wish to create more embryos than are required for implantation because they are uncomfortable with concept of unused leftover embryos. The Caudills used the remaining eggs, which had been frozen for research purposes, as a last resort.

The Mayo Clinic now offers egg-freezing to women, including those who wish to delay pregnancy, for double the price of frozen-embryo storage – at roughly £500 – and makes it clear that the success rates is much lower to conceive children using this method. Only half of frozen eggs survive the thawing process. Then 10-15 per cent of those thawed eggs successfully lead to live births where as frozen embryos have a 50 per cent chance of leading to a live birth at the clinic. They use a technique that removes much of the water in the eggs before slowly freezing them and later thaw them slowly returning the water to the eggs for re-absorption.

The California couple had attempted every possible IVF combination, using both of their eggs, and was ‘exhausted’. After five unsuccessful attempts they were just trying to hedge their bets to successfully have a single child but were delighted to learn that they were each pregnant and that they were both having twins. The two sets of twins were surprisingly born only 22 hours apart. The couple is ‘thrilled, knowing they’re all related and can help each other through life’.

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